Network Explorer

来源:百度文库 编辑:神马文学网 时间:2024/06/07 21:06:02

Network Explorer

Network Explorer is a powerful tool for visualizing molecular relationships.  It displays an interactive graphical representation of the interrelationships between molecules.  

 

Genes, proteins, and chemicals are displayed as various shapes. The shapes are indicative of the molecular class (protein family, or chemical). Double clicking on a molecule will display the Molecule Summary View. Coloring is based on the expression values that were uploaded with the dataset. As a default, red indicates up-regulation (positive values), green indicates down-regulation (negative values), gray indicates the molecule was part of the dataset but did not meet the user-specified cutoff value, and white indicates the molecule was added from the Ingenuity Knowledge Base.

 

Lines connecting molecules indicate molecular relationships. There are two line styles. Dashed lines indicate indirect interactions; solid lines indicate direct interactions. The style of the arrows indicate specific molecular relationships and the directionality of the interaction (A acts on B). Double clicking on an edge displays the Relationship Summary view.

 

For more details, please refer to the IPA Legend.

 

Navigating Network Explorer

To view the network from the Analysis Results Summary page either:

1)   Click on the network ID,

 

or

 

1)   Select the checkbox next to the network ID column.

2)   Click the View Networks button.

 

This launches Network Explorer, and you will see a schematic diagram of the network you have selected to view, as shown below.

 

 

When viewing multiple networks you can use the tabs at the top of the Network Explorer frame to navigate between them.

 

3. Select a node and right click for shortcuts to several options.  You can select show members to see the individual members of a protein complex.